3-O-Methylgallic acid
CAS No. 3934-84-7
3-O-Methylgallic acid ( 3,4-Dihydroxy-5-methoxybenzoic acid; 3,4-Dihydroxy-5-methoxybenzoic acid )
Catalog No. M29069 CAS No. 3934-84-7
3,4-Dihydroxy-5-methoxybenzoic acid reduces cell proliferation in Caco-2 cells(IC50 = 24.1 μM) more effectively than anthocyanins and may offer protection against colon cancer after its formation in the gut. 3,4-Dihydroxy-5-methoxybenzoic acid inhibits transcription factors NF-κB, AP-1, STAT-1, and OCT-1 which are known to be activated in colorectal cancer.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
100MG | 27 | In Stock |
|
500MG | 58 | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
-
Product Name3-O-Methylgallic acid
-
NoteResearch use only, not for human use.
-
Brief Description3,4-Dihydroxy-5-methoxybenzoic acid reduces cell proliferation in Caco-2 cells(IC50 = 24.1 μM) more effectively than anthocyanins and may offer protection against colon cancer after its formation in the gut. 3,4-Dihydroxy-5-methoxybenzoic acid inhibits transcription factors NF-κB, AP-1, STAT-1, and OCT-1 which are known to be activated in colorectal cancer.
-
Description3,4-Dihydroxy-5-methoxybenzoic acid reduces cell proliferation in Caco-2 cells(IC50 = 24.1 μM) more effectively than anthocyanins and may offer protection against colon cancer after its formation in the gut. 3,4-Dihydroxy-5-methoxybenzoic acid inhibits transcription factors NF-κB, AP-1, STAT-1, and OCT-1 which are known to be activated in colorectal cancer.(In Vitro):3,4-Dihydroxy-5-methoxybenzoic acid(10-100 μM) caused a time- and dose-dependent decrease in cell viability.
-
Synonyms3,4-Dihydroxy-5-methoxybenzoic acid; 3,4-Dihydroxy-5-methoxybenzoic acid
-
PathwayApoptosis
-
TargetApoptosis
-
RecptorApoptosis
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number3934-84-7
-
Formula Weight184.1
-
Molecular FormulaC8H8O5
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCOc1cc(cc(O)c1O)C(O)=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
molnova catalog
related products
-
Britannin
Britannin a sesquiterpene lactone inhibits proliferation and induces apoptosis through the mitochondrial signaling pathway in human breast cancer cells.
-
Ganoderenic acid D
Ganoderenic acid D is a natural product isolated from the effective compounds of Ganoderma lucidum extract (GLE). Ganoderenic acid D induces cell cycle arrest and apoptosis and inhibits the proliferation of cancer cells.
-
Merodantoin
Merodantoin is an apoptosis inducer and triggers cell apoptosis associated with ROS-dependent autophagy. Merodantoin targets cancer cells expressing KRAS mutations involved in Akt-dependent ROS production.